CNN gained exclusive access to the facility, now home to Generium Pharmaceutical, which was contracted to increase production of the Russian Covid-19 vaccine, Sputnik V.
The vast high-tech complex is one of seven new production centers across the country.
Each step of the production process had to be carefully designed and calibrated, including vast water filtration systems, to mass produce the new vaccine.
“In principle, the manufacturing process was known on a small laboratory scale, but doing it on a large industrial scale is another universe,” Dmitry Poteryaev, director of science at Generium, told CNN.
“You can’t just go from one liter of bioreactor to 100 liters or 1000 or 1 ton of bioreactor. Each process is different, oxygenation is different, the mass balance is different ”, he explained.
He said that these problems were overcome several months ago and that the factory is now ready to further increase production.
“Now, we are producing several million doses per month and we hope to get even more, perhaps around 10 or 20 million per month,” said Poteryaev.
In cavernous refrigerators, with temperatures even colder than the freezing winter in Russia, vials of Sputnik V are packed in crates, awaiting distribution. Each bottle has its own unique QR code, we are informed, so that it can be tracked down to individual patients, no matter where they are.
Hesitation at home
This is a country with one of the highest numbers of Covid-19 infections in the world – over 4.1 million cases and counting. But it also has one of the highest vaccine hesitation rates in the world. A recent opinion poll, published by the independent Levada Center, indicated that only 38% of Russians want to be vaccinated.
Earlier this month, one of the leading scientists behind the vaccine’s development said that about 2.2 million people – less than 2% of the Russian population – received at least the initial dose of the two-dose regimen.
Still, anti-vaccine conspiracy theories are running wild on the internet and seen by millions in Russia, according to monitoring groups. Alexander Arkhipova, a social anthropologist at a state university known as RANEPA, told CNN that many Russians have a cultural tendency to distrust the medical establishment, which is seen as a controlling arm of the government, interfering in people’s private lives.
Another reason for doubt may be that, although President Vladimir Putin said his daughter was vaccinated, he has not yet applied the vaccine.
The Kremlin rejected questions about why, saying Putin has a scheduled vaccine and that when he gets vaccinated, the nation will be informed.
But in a country where many people turn to the Kremlin strongman for his leadership, his abstinence in front of Sputnik V is remarkable and disheartening.
Ice cream incentives
All adults without underlying health conditions in Russia are now eligible for a free vaccination. But progress in Moscow, for example, is painfully slow. In a city with more than 12 million inhabitants, less than 600,000 have been vaccinated so far, according to Mayor Sergey Sobyanin.
So, the impetus is to increase the numbers.
And in Moscow – the epicenter of Russia’s coronavirus pandemic – emerging clinics are being set up.
There is one at the luxurious GUM shopping center, a short walk from snowy Red Square, where Muscovites can read the latest news in expensive boutiques before going up to buy Sputnik V. They even get free ice cream with every inoculation – coated with vanilla chocolate .
Officials told CNN that they were vaccinating about 200 people every day. There is capacity for hundreds more.
Another clinic was set up in a trendy cafeteria, Depo Moscow, to encourage vaccination after a street food lunch or sushi dinner.
For lovers of classical music, there is even one inside Helikon, a prestigious Moscow opera house, where austere tones of recorded tenors sound over the speakers while people wait for their inoculation.
Some people are getting the message that the vaccine is the best chance of surviving the pandemic.
Vadim Svistunov, 84, and his wife, Nonna, 86, went to the theater for the initial injection of the vaccine and for the booster three weeks later.
“We don’t want to go up there yet,” Svistunov told CNN, as he gestured to the sky. “We are not in a hurry,” he said.