The 49ers have 17 injured players in reserve and two others, center Weston Richburg and striker Ronald Blair, who has spent the entire season on the list of physically unable to play.
In addition, seven more players from the 53-man squad were officially prevented from preparing for the 49ers’ season final on Sunday against the Seattle Seahawks in Glendale, Ariz.
Among those on the aforementioned lists, it seems likely that NFL All-Decade cornerback Richard Sherman, edge rusher Dee Ford and Richburg have already played their final games with the 49ers. And with a total of 27 players scheduled for an unrestricted free agency, there will be some players who won’t be back in 2021.
Here’s a look at six players who may be playing Sunday with 49ers for the last time.